Michigan Diagnostic Pathologists
Michigan Diagnostic Pathologists, PLLC
Affiliated with: Ascension Providence - Providence Park Hospitals, Southfield and Novi Campuses
 
Acute Appendicitis
Acute Appendicitis

Acute appendicitis is inflammation of the appendix, a small pouch that hangs off of the beginning of the large intestine. Thus usually occurs due to an obstruction and can become infected.

In this image, the various layers of the appendix can be seen. The purplish haze seen through the appendiceal layers is evidence of the inflammatory cells.

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Cholangiocarcinoma
Cholangiocarcinoma

Cholangiocarcinoma is a cancer of the biliary tree; a system of ducts that carries bile from the liver to the small intestine where it is used to aid in digestion.

In image 2, the ducts, which appear as large circular structures, are disorganized with irregular lumens. The nuclei of their cells, which appear as smaller dark purple structures, show variation in shape and size when in normal ducts they should be the same size and shape. In image 3, the ducts are again disorganized. In this image, mucinous secretions are more evident than in image 2.

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Cholangiocarcinoma
Cholangiocarcinoma

Cholangiocarcinoma is a cancer of the biliary tree; a system of ducts that carries bile from the liver to the small intestine where it is used to aid in digestion.

In image 2, the ducts, which appear as large circular structures, are disorganized with irregular lumens. The nuclei of their cells, which appear as smaller dark purple structures, show variation in shape and size when in normal ducts they should be the same size and shape. In image 3, the ducts are again disorganized. In this image, mucinous secretions are more evident than in image 2.

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Hairy Cell Leukemia
Hairy Cell Leukemia

Hairy cell leukemia is a cancer of a type of white blood cell called the B-cell. Hairy cell leukemia involves the peripheral blood, bone marrow, liver and spleen.

In this image, near the center of the field, are several cells with round, bland nuclei and abundant pale cytoplasm. Sometimes this cytoplasm can have multiple thin projections, hence the name hairy cell leukemia.

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Congo Red Positive Amyloid Deposits in the GI Tract
Congo Red Positive Amyloid Deposits in the GI Tract

Amyloid deposits are insoluble collections of misfolded proteins. These misfolded proteins can be involved in a number of disease processes including amyloidosis, Alzheimer’s disease, rheumatoid arthritis and many more.

In this image, the amyloid deposits are highlighted by a special stain called Congo Red which gives them a bright red-orange color under standard microscopy. Under polarized light the amyloid will have an apple-green color.

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PATHOLOGY SERVICES

Why do I need a Pathologist? Pathologists work in conjunction with primary care physicians and specialists by providing crucial tests results needed by the physician to determine a particular diagnosis. By providing diagnostic results, we provide your physician the information he or she needs to diagnose and treat a condition. Typically, your physician will send your blood or tissue biopsy sample to us and ask that we perform any of a variety of tests on it. These tests are performed in a laboratory, often in a hospital. We then report the results back to your personal physicians, usually in a few days. The physician will then use that information to help provide your care. Additional details about our services are also available.

How can I get my results? When testing on anyblood or tissue sample is complete, a report will be sent to physicians involved in your care. Your own physician may be the best person to help you understand the results and provide answers to your questions about any future treatment that might be needed. Reports on blood or tissue biopsy specimenswhen the testing was performed at Ascension Providence-Providence Park Hospitals, Southfield and Novi campuses can be obtained from the Pathology office at Ascension Providence-Providence Park Hospital in Southfield. Reports on blood or tissue biopsy specimens when the testing was performed at Garden City Hospital can be obtained from the Pathology office at Garden City Hospital, Garden City. Due to privacy concerns, specific results cannot be released over the phone. A signed releasemay be required. Please visit the “Contact Us” page for specific phone numbers.

FOR HEALTH CARE PROVIDERS